Here Are Some Questions That Can Make It Easier To Talk To Your Doctor

Who should not take MULTAQ?

Do not take MULTAQ if you have symptoms of heart failure which have recently worsened or if you have severe heart failure. People with these conditions who take MULTAQ have an increased chance of dying.

Do not take MULTAQ if you have a type of atrial fibrillation (AFib) called permanent AFib. You should not take MULTAQ if you are in AFib and your doctor is not planning to change you back into normal rhythm.

When should I call the doctor?

Call your doctor immediately if you're taking MULTAQ and have any signs and symptoms of heart failure. These may include shortness of breath or wheezing at rest; wheezing, chest tightness, or coughing up frothy sputum at rest, nighttime, or after minor exercise; trouble sleeping or waking up at night or using more pillows to prop yourself at night because of breathing problems; weight gain; or foot or leg swelling.

Call your doctor right away if you notice that your heartbeat or pulse is irregular. This is a sign that you are in AFib.

What other serious risks should I discuss with my doctor?

MULTAQ may cause liver problems, including life-threatening liver failure. Tell your doctor right away if you are taking MULTAQ and develop any of these signs and symptoms of liver problems: loss of appetite; nausea; vomiting; fever; feeling unwell; unusual tiredness; itching; yellowing of the skin or the whites of the eyes; unusual darkening of the urine; right upper stomach area pain or discomfort.

An additional serious side effect is a slowed heartbeat.

Who else shouldn't take MULTAQ?

You should not take MULTAQ if you have severe liver problems or if you had liver problems after using amiodarone.

You should not take MULTAQ if you are breastfeeding, pregnant, or plan to become pregnant as it is not known if it may pass to or harm your baby. Women who may become pregnant should use effective birth control while taking MULTAQ. Talk to your doctor about the best birth control methods for you.

Are there any medications I should avoid while taking MULTAQ?

MULTAQ can interact with certain medications. Do not use the following medications with MULTAQ:

• Nefazodone
• Ritonavir
• Ketoconazole
• Itraconazole
• Voriconazole
• Telithromycin
• Clarithromycin
• Cyclosporine

Are there other medicines that would be harmful when taken with MULTAQ?

The following medicines can lead to a dangerous abnormal heart rhythm if taken with MULTAQ:

• Phenothiazines
• Tricyclic antidepressants
• Certain medicines used to treat an abnormal heart rhythm or fast heartbeat
• Certain antibiotics

Is it OK to take a diuretic ("water pill") while on MULTAQ?

Your potassium levels should be within the normal range prior to and while taking MULTAQ. Tell your doctor about any diuretic medications ("water pills") you are taking as some can lower the level of potassium or magnesium in your blood.

What are the most common side effects?

The most common side effects when taking MULTAQ include stomach problems such as diarrhea, nausea, vomiting, stomach area pain, and indigestion; feeling tired and weak; skin problems such as redness, rash, and itching. Tell your doctor about any side effect that bothers you or that does not go away.

Are there other things I should avoid while taking MULTAQ?

Do not drink grapefruit juice while taking MULTAQ, as this can increase the likelihood that you will have a side effect of MULTAQ.

What else should I tell my doctor?

Tell your doctor about all medications, vitamins, and herbal remedies (including St. John's Wort) you take to help avoid serious drug interactions.

Will I need any tests while I'm on MULTAQ?

Your doctor will monitor your heart rhythm regularly to make sure your heartbeat keeps a normal rhythm. Your doctor may perform certain tests, such as heart exams and blood tests, while you're taking MULTAQ.

Full Prescribing Information Including boxed WARNING

MULTAQ Medication Guide (English)

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